Whole genome analysis for QTL/association enrichment
Running...
Version: Enrich S: beta v0.8
Data:
Number of disease susceptibility traits:
29
Number of QTL / associations found:
665
Number of chromosomes where QTL / associations are found:
19
Chi-squared (χ2) test: are disease susceptibility traits over-represented on some chromosomes?
Chromosomes
Total χ2
df
p-values
FDR *
Size of χ2
Chromosome X
745.71441
18
1.112722e-146
1.057086e-145
Chromosome 1
119.31441
18
5.652934e-17
7.160383e-17
Chromosome 2
3.31441
18
0.9999408
9.999408e-01
Chromosome 3
299.11441
18
7.324431e-53
1.988060e-52
Chromosome 4
2598.40000
18
9e-41
1.710000e-40
Chromosome 5
268.45706
18
1.409293e-46
3.347071e-46
Chromosome 6
29.82853
18
0.03914727
4.648738e-02
Chromosome 7
3.31441
18
0.9999408
9.999408e-01
Chromosome 8
186.42853
18
5.086292e-30
6.902825e-30
Chromosome 9
239.45706
18
1.128188e-40
1.786298e-40
Chromosome 10
365.40000
18
1.45251e-66
6.899422e-66
Chromosome 11
299.11441
18
7.324431e-53
1.988060e-52
Chromosome 12
239.45706
18
1.128188e-40
1.786298e-40
Chromosome 13
18892.25706
18
9e-41
1.710000e-40
Chromosome 14
0.82853
18
0.998329325823115
9.999408e-01
Chromosome 15
745.71441
18
1.112722e-146
1.057086e-145
Chromosome 16
696.82853
18
2.672468e-136
1.692563e-135
Chromosome 17
186.42853
18
5.086292e-30
6.902825e-30
Chromosome 18
331.42853
18
1.591911e-59
6.049262e-59
Chi-squared (χ2) test: Which of the 29 disease susceptibility traits are over-represented in the QTLdb
Traits
Total χ2
df
p-values
FDR *
Size of χ2
ADV antibody titer
19.5413
28
0.8806053
9.822136e-01
Actinobacillus pleuropneumoniae susceptibility
315.63208
28
1.905981e-50
5.527345e-49
Anti-K88 E.coli IgG levels
38.11766
28
0.0961934
2.145853e-01
Anti-O149 E.coli IgG level response
21.93104
28
0.7844738
9.822136e-01
Anti-O149 E.coli IgG levels
21.93104
28
0.7844738
9.822136e-01
Antibody response to Brucella suis
75.6502
28
2.913153e-06
1.689629e-05
Brucellosis susceptibility
26.87992
28
0.5247932
8.455002e-01
CSFV antibody level
33.75213
28
0.2091535
4.043634e-01
Change in Mycoplasma hyopneumoniae antibody titer
42.38726
28
0.03984844
9.630040e-02
Change in tetanus antibody titer
43.33334
28
0.03230689
8.517271e-02
Chronic pleuritis susceptibility
20.12113
28
0.8600087
9.822136e-01
Enterotoxigenic E. coli susceptibility
310.385
28
2.115981e-49
3.068172e-48
Leptospirosus susceptibility
21.09881
28
0.8212053
9.822136e-01
Melanoma susceptibility
62.6648
28
0.0001839636
6.668681e-04
Mycoplasma hyopneumoniae antibody titer
28.73856
28
0.4258766
7.719013e-01
Mycoplasmal pneumonia susceptibility
65.21741
28
8.42538e-05
3.490515e-04
PRRS viral load
65.21832
28
8.423008e-05
3.490515e-04
PRRSV antibody titer
138.08871
28
1.650743e-16
1.196789e-15
PRRSV susceptibility
60.9326
28
0.000309154
9.961629e-04
Periweaning failure to thrive syndrome
194.05631
28
9.084343e-27
8.781532e-26
Postpartum dysgalactia syndrome susceptibility
16.41265
28
0.9593068
9.887432e-01
Pseudorabies susceptibility
27.04064
28
0.5160348
8.455002e-01
Pseudorabies virus antibody titer
13.98685
28
0.9872816
9.887432e-01
Rhinitis susceptibility
13.76974
28
0.9887432
9.887432e-01
Sarcocystis miescheriana IgG levels
44.27443
28
0.02609455
7.567419e-02
Sarcocystis miescheriana IgM levels
23.54581
28
0.7052662
9.822136e-01
Small intestinal Escherichia coli F18 receptor
21.93104
28
0.7844738
9.822136e-01
Tetanus antibody titer
24.32102
28
0.6644833
9.822136e-01
Tuberculosis susceptibility
36.6584
28
0.1265870
2.622159e-01
Correlations found between some of these traits for your reference
No correlation data found on these traits
Overall Test
Data
Chi'Square Test
Fisher's Exact Test
Number of chrom.:
19
χ2
=
26250.800290
Number of traits:
29
df
=
504
Number of QTLs:
665
p-value
=
0
FOOT NOTE: * : FDR is short for "false
discovery rate", representing the expected proportion of type I errors. A type I
error is where you incorrectly reject the null hypothesis, i.e. you get a false
positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where
V = Number of Type I errors (false positives); R = Number of rejected hypotheses.
Benjamini–Hochberg procedure is a practical way to estimate FDR.
Running...
